The emergence of variant strains is accelerating: When does the industry need tailored solutions?

{"ops":[{"insert":"Over the past two decades, intensive production systems for poultry, swine, ruminants and aquaculture have reached exceptional levels of efficiency. However, this very intensification is leading to a phenomenon that is redefining health challenges on a global scale.\n\nThe combination of vaccination pressure, high animal density, continuous movement of flocks, and standardized health programs is favoring the emergence of new antigenic variants, many of which exhibit different productive and epidemiological behaviors than expected.\n\nIn highly integrated systems, this environment fosters:\nThe emergence of strains with significant genetic divergence."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Production failures without characteristic clinical signs."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Decreased effectiveness of traditional health programs."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"A growing antigenic gap between circulating viruses and commercially available vaccines."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"\nThis is not an isolated phenomenon. It is a well-established trend in intensive systems worldwide.\n\nWhen biology advances faster than the tools, science must respond at the same speed"},{"attributes":{"header":2},"insert":"\n"},{"insert":"\nAt Benten Biotech, we have worked on numerous cases where companies in various production sectors faced:\nPersistent mortality with no apparent cause."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Decreases in egg production, weight gain, or feed conversion."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Incomplete or inconsistent vaccine responses."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Subclinical conditions with cumulative economic impact."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Viral challenges that did not correspond to the traditional profiles detected in the laboratory."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"\nIn all these cases, the same pattern emerged: the available tools were not designed for the viral variant actually circulating in the field.\n\nThe integration of advanced molecular diagnostics, genomic surveillance, and applied biotechnology made it possible to identify the root cause and design precise solutions based on the biology of the challenge.\n\nWe will present three real cases"},{"attributes":{"header":2},"insert":"\n"},{"insert":"\nIn future publications, we will share three examples from integrated egg production, swine production, and aquaculture operations.\n\nIn all of them, the health managers arrived with the same concern: “We don’t know exactly what is affecting our production, but the problem persists.”\n\nThrough a rigorous scientific approach, we were able to:\nIdentify the variant responsible for the condition."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Determine its antigenic distance from the commercial vaccine spectrum."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Explain why traditional health programs were not working."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Develop biologics specifically formulated for this particular challenge."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"Restore the health stability and production predictability of the system."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"\nA message for the industry"},{"attributes":{"header":2},"insert":"\n"},{"insert":"\nAnimal health faces a critical transition. Generic tools are no longer sufficient to address the biological complexity emerging in modern intensive farming systems.\n\nThe future demands a new paradigm:\nFrom standard solutions to precision solutions."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"From generalized programs to programs based on the specific variant of each system."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"From reactive responses to strategies that anticipate challenges from a genomic perspective."},{"attributes":{"list":"bullet"},"insert":"\n"},{"insert":"\nVariants will continue to emerge.\n\nThe competitiveness of each company will depend on its ability to detect them promptly and respond with tools specifically designed for them.\n\nAt Benten Biotech, we work under this model:\nIn-depth diagnosis → development of customized biologics → recovery and production stabilization.\n"}]}